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Within-Subject Changes In MADRS Scores Are Correlated With Changes In Audio-Video Digital Traits In Major Depressive Disorder

  • Patients with major depressive disorder (MDD) exhibit changes in voice, speech, and movement, compared to healthy controls in research settings.
  • Yet, little is known about how digital measures collected via smartphone-based assessments change longitudinally with clinical measures of symptom severity.
  • Here, we report the results of a change score analysis between digital A/V measures collected in naturalistic settings and MDD clinical scores