Clinical trial participant medication adherence captured with advanced technology is predictive of early termination (ET). Ongoing data monitoring and effective site- and participant-interventions are needed to unlock improved retention outcomes.

 

• Participants who are adherent with AiCure only (not including CSS central monitoring) are 17.4% less likely to early terminate compared to those who are non-adherent. 
• Furthermore, just the first 14 days of AiCure captured medication adherence can accurately predict the likelihood of a participant completing the study. 
• The results show CSS reduced early termination rates for adherent participants is only 7.8%. 
• The ISCTM poster from last year (2024) already demonstrated that CSS improves medication adherence rates overall, with more participants achieving high adherence.
• Using a 14 day lead-in period capturing adherence via the Platform would be a data-driven strategy to ensure participants who are likely to be adherent and retained are randomized.